Sero tsika inzira yekuti masero ararame, akure, abereke uye achengetedze iwo makuru zvimiro nemabasa nekutevedzera nharaunda mu vivo in vitro.Sero tsika bhodhoroimhando yesero rinoshandiswa rinowanzoshandiswa mune adherent cell tsika.Mukuita kwesero tsika, kazhinji tinowana kumwe kusvibiswa kuunganidzwa mumvura.Pane zvikonzero zvakawanda zvemamiriro ezvinhu aya, uye tembiricha zvakare chimwe chezvikonzero zvinowanzoitika.
Kuvapo kwekunaya kwemvura mucell culture flask kungave mhedzisiro yekusvibiswa kwesero.Kana kusvibiswa kukasabatanidzwa, turbidity musero tsika svikiro inowanzodudzirwa sekunaya kwezvinhu zvesimbi, mapuroteni, uye zvimwe zviri pakati nepakati.Mazhinji anokonzeresa anokanganisa kupararira kwesero nekuti anoshandura kuumbwa kwepakati nechelating nutrients nezvimwe zvinodiwa.Iyo precipitate inogona kucherechedzwa microscopically uye inogona kukanganisa miedzo inoda kuongororwa kwekufungidzira.
 
Muchitokisi tsika, tembiricha ndicho chimwe chezvinhu zvinokonzeresa kunaya kwemvura.Kana tembiricha yachinja zvakanyanya, yakakwira molecular uremu plasma mapuroteni anozotorwa kubva mumhinduro.Kupisa kusashanda uye kutonhora-kunyorova kutenderera kunogona kukurudzira kuderera kweprotein uye kunaya.Nekuti iyo mvura kana yakagadziridzwa svikiro inochengeterwa munzvimbo inotonhora pakati pekushandisa, munyu unogona kugadzikana, kunyanya mu10X kana mamwe magadzirirwo akadzikama ekuchengetedza.
 
Ehe, kunaya kwemvura kunoonekwa musero tsika bhodhoro.Kana zvakatemwa kuti tembiricha ndiyo honzeri, kutarisisa kunofanirwa kubhadharwa kunharaunda yekuchengetera uye nzira yekushanda yetsika yepakati kudzivirira kutonhora kudzokororwa uye kunyungudika, izvo zvinogona kuderedza mukana wekunaya kwemvura.