Sero mabhodhoro etsikaanowanzo shandiswa mune adherent cell tsika, uko maseru anofanirwa kusungirirwa pamusoro pechinhu chinotsigira kuti akure.Zvino chii chinokwezva chiri pakati pesero rinobatirira nechinhu chinotsigira, uye chii chinonzi mashandiro esero rinonamatira?

Cell adhesion inoreva maitiro ekunamatira anotsamira maseru anonamira uye achipararira pamusoro petsika.Kana sero rinogona kubatanidzwa kune tsika yepasi kunoenderana nehunhu hwesero pachayo, pakuonana kungangoitika pakati pesero netsika yepasi, uye pakuenderana pakati pesero uye tsika yepasi, iyo ine hukama nekemikari uye. zvinhu zvemuviri zvepamusoro.

Iyo sero yekunamatira mwero inoenderanawo nemakemikari uye emuviri zvimiro zvehutsika hwepasi, kunyanya iyo yekuchaja density pane tsika yepasi.Iyo inotonhora uye fibronectin muserum inogona kubhuroka tsika pamusoro pesero, izvo zvinobatsira kumhanyisa chiyero chekunamatira sero.Mukuwedzera kune zvikonzero zviri pamusoro apa, kupararira kwemasero pamusoro petsika yepamusoro kunobatanidzawo nemamiriro ezvinhu epamusoro, kunyanya kutsetseka.

Masero akawanda emammalian anokura mu vivo uye in vitro akabatanidzwa kune mamwe ma substrates, ayo mu vitro anogona kuva mamwe masero, collagen, mapurasitiki, etc. Masero anotanga secrete extracellular matrix, iyo inonamatira pamusoro pesero tsika vial.Sero rinobva rasunga kune aya ekunze matrices kuburikidza neadhesion zvinhu zvinoratidzwa pamusoro payo.

Uye zvakare, kuitira kusimudzira zvirinani kuomerera kwesero, iyo yekukura pamusoro pesero tsika bhodhoro inozonyatso kurapwa kuunza hydrophilic mass, ayo anofambisa kukura kwemaseru anoomerera.