Muchitokisi tsika,sero tsika bhodhoroinowanzoshandiswa mumudziyo, inoshandisa yakakura mutsipa dhizaini, iri nyore kushanda.Kukura kwemasero kunoda mamiriro chaiwo, ayo mamiriro asina utachiona akakosha zvikuru.

Nontoxicity uye sterility ndiwo mamiriro ekutanga emaseru akagadzirwa mu vitro.Mu vivo, iyo detoxification system uye immune system inogona kuramba kupinda kwehutachiona kana zvimwe zvinhu zvinokuvadza, asi mukuita kwesero tsika in vitro, senge cell tsika bhodhoro, kushomeka kwekudzivirira immune system uye kurasikirwa kweiyo microbial kudzivirira kugona uye detoxification. kukwanisa kune zvinhu zvinokuvadza.Kuve nechokwadi chekuti maseru anogona kukura nekuberekana munzvimbo yekunze, zvinodikanwa kuve nechokwadi chenzvimbo yebasa isina hutachiona, hutsanana hwemunhu, sterile reagents uye midhiya, uye kubata kusingabereki.

Ehe, aseptic nharaunda ingori imwe yeakakosha mamiriro echitokisi tsika musero tsika bhodhoro.Zvimwe zvinosanganisira tembiricha chaiyo, osmotic pressure, uye PH yenzvimbo yegasi, ari iwo mamiriro ekutanga anodiwa pakukura kwesero.

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